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WHAT IS AIDS? Causes, Symptoms, Diagnosis, Treatment


WHAT IS AIDS?
AIDS is the most advanced stage of HIV infection. Once HIV infection develops into AIDS, infections and cancer pose a greater risk.
Without treatment, HIV infection is likely to develop into AIDS as the immune system gradually wears down. However, advances in ART mean than an ever-decreasing number of people progress to this stage.
By the close of 2015, around 1,122,900 people were HIV-positive. To compare, figures from 2016 show that medical professionals diagnosed AIDS in an estimated 18,160 people.

Causes
People transmit HIV in bodily fluids, including:
  • blood
  • semen
  • vaginal secretions
  • anal fluids
  • breast milk
In the United States, the main causes of this transfer of fluids are:
  • anal or vaginal intercourse with a person who has HIV while not using a condom or PrEP, a preventive HIV medication for people at high risk of infection
  • sharing equipment for injectable illicit drugs, hormones, and steroids with a person who has HIV
A woman living with HIV who is pregnant or has recently given birth might transfer the disease to her child during pregnancy, childbirth, or breastfeeding.
The risk of HIV transmitting through blood transfusions is extremely low in countries that have effective screening procedures in place for blood donations.

Symptoms

For the most part, infections by other bacteria, viruses, fungi, or parasites cause the more severe symptoms of HIV.
These conditions tend to progress further in people who live with HIV than in individuals with healthy immune systems. A correctly functioning immune system would protect the body against the more advanced effects of infections, and HIV disrupts this process.

Early symptoms of HIV infection

Some people with HIV do not show symptoms until months or even years after contracting the virus.
However, around 80 percent of people may develop a set of flu-like symptoms known as acute retroviral syndrome around 2–6 weeks after the virus enters the body.
The early symptoms of HIV infection may include:
  • fever
  • chills
  • joint pain
  • muscle aches
  • sore throat
  • sweats. particularly at night
  • enlarged glands
  • a red rash
  • tiredness
  • weakness
  • unintentional weight loss
  • thrush
These symptoms might also result from the immune system fighting off many types of viruses.
However, people who experience several of these symptoms and know of any reason they might have been at risk of contracting HIV over the last 6 weeks should take a test.

Asymptomatic HIV

In many cases, after the symptoms of acute retroviral syndrome, symptoms might not occur for many years.
During this time, the virus continues to develop and cause immune system and organ damage. Without medication that prevents the replication of the virus, this slow process can continue for an average of around 10 years.
A person living with HIV often experiences no symptoms, feels well, and appears healthy.
Complying rigidly to a course of ART can disrupt this phase and suppress the virus completely. Taking effective antiretroviral medications for life can halt on-going damage to the immune system.

Late-stage HIV infection

Without medication, HIV weakens the ability to fight infection. The person becomes vulnerable to serious illnesses. This stage is known as AIDS or stage 3 HIV.
Symptoms of late-stage HIV infection may include:
  • blurred vision
  • diarrhea, which is usually persistent or chronic
  • dry cough
  • a fever of over 100 °F (37 °C) lasting for weeks
  • night sweats
  • permanent tiredness
  • shortness of breath, or dyspnea
  • swollen glands lasting for weeks
  • unintentional weight loss
  • white spots on the tongue or mouth
During late-stage HIV infection, the risk of developing a life-threatening illness increases greatly. A person with late-stage HIV can control, prevent and treat serious conditions by taking other medications alongside HIV treatment.

HIV and AIDS myths and facts

Many misconceptions circulate about HIV that are harmful and stigmatizing for people with the virus.
The following cannot transmit the virus:
  • shaking hands
  • hugging
  • kissing
  • sneezing
  • touching unbroken skin
  • using the same toilet
  • sharing towels
  • sharing cutlery
  • mouth-to-mouth resuscitation or other forms of "casual contact"
  • the saliva, tears, feces, and urine of a person with HIV

Diagnosis

The Centers for Disease Control and Prevention (CDC) estimates that about 1 in every 7 HIV-positive Americans is unaware of their HIV status.
Becoming aware of HIV status is vital for commencing treatment and preventing the development of more severe immune difficulties and subsequent infections.

HIV blood tests and results

A doctor can test for HIV using a specific blood test. A positive result means that they have detected HIV antibody in the bloodstream. The blood is re-tested before a positive result is given.
After potential exposure to the virus, early testing and diagnosis is crucial and greatly improves the chances of successful treatment. Home testing kits are also available.
HIV might take 3 - 6 months to show up in testing, and re-testing may be necessary for a definitive diagnosis. People at risk of infection within the last 6 months can have an immediate test. The test provider will normally recommend another test within a few weeks.

Treatment

No cure is currently available for HIV or AIDS.
However, treatments can stop the progression of the condition and allow most people living with HIV the opportunity to live a long and relatively healthy life.
Starting ART early in the progression of the virus is crucial. This improves quality of life, extends life expectancy, and reduces the risk of transmission, according to the WHO's guidelines from June 2013.
More effective and better-tolerated treatments have evolved that can improve general health and quality of life by taking as little as one pill per day.
A person living with HIV can reduce their viral load to such a degree that it is no longer detectable in a blood test. After assessing a number of large studies, the CDC concluded that individuals who have no detectable viral load "have effectively no risk of sexually transmitting the virus to an HIV-negative partner."


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